UPM Pharmaceuticals Manufacturing Facility

Family Legacy. Big Pharma Portfolio

Situated on nearly seven acres in historic Bristol, Tennessee, is UPM Pharmaceuticals’ 475,000-square-foot commercial manufacturing facility with capacity to produce millions of units of drug product annually.

This state-of-the-art facility has been primarily owned and operated by the UPM family legacy since its acquisition in the early nineties, and has since seen the successful scale-up of over 80 products to commercialization. Today, the facility continues to supply several commercial products, with the capacity to produce 700 million capsules, 4 billion tablets and 1,300,000 kilogram units of semi-solids for customers each year.

For 17 years, one of the most stable pharmaceutical companies in the US—King Pharmaceuticals—manufactured a portfolio of successful commercial products from the UPM facility. The site was also briefly owned and operated by Pfizer.

Facility Snapshot

The UPM site conducts large-scale commercial manufacturing and packaging of semi-solid creams and ointments as well as OSD drug product. Flexibly designed to provide full tech transfer and scale-up support, the facility has an extensive track record of optimizing processes to achieve commercial success. In addition to its production capacity, the site is also equipped to handle analytical, microbial and stability testing, with a full-service analytical laboratory to support the production of solids and semi-solids at all scales.

The site is DEA-licensed for Schedule II–V controlled substances and has over 15,800 square feet of DEA Approved vault space total.

Come Visit Us Today

At UPM, our partnerships thrive on transparency, as our doors are always open. We invite you to come to visit us in beautiful Bristol, Tennessee, tour our facility and sit down with our Executive Team to discuss how your project goals align with our capabilities and capacity.

Controlled Substance Handling

UPM has a number of strict controls in place to ensure the safe handling of DEA Schedule I–V controlled substances and listed chemicals—chief among them being customer and staff education. We take very seriously our responsibility to safely develop your product while navigating the regulatory pathway on your behalf. Working in close collaboration with customers, we ensure you not only understand all relevant Controlled Substances Act (CSA) regulations, but also the specific implications of those regulations on your product and market strategy.