(423) 989-8000     info@upm-inc.com

Proof of Concept

UPM’s Brevi-Batch mini-scale equipment and customized R&D facility provide for a broad range of formulations and processing to support early stage proof of concept. Separate processing suites, walk in down flow areas and hoods allow for the utmost in safety and efficiency for early stage compounds.

Formulation Development

UPM has small scale and pilot size equipment for solid dose formulation development including high shear granulation, fluid bed granulation and drying, roller compaction, extrusion-spheronization, beads, encapsulation, mini-tablets, bi-layer tablets and coating. This broad range of processing allows for immediate release, delayed release, enteric release and other combination products.

Analytical Services

UPM’s analytical laboratories support client testing needs from development to commercial, including method development, transfer and validation, incoming raw material release, compendial testing, product release testing, stability study management & testing and microbial limit testing.

Clinical Manufacturing

UPM can manufacture small to mid-size batches for clinical Phase I, II and III, including raw material and release testing. Our equipment is sized for efficient use and change over for small scale batches. We have a semi-automated packaging and labeling line designed to complement the unique challenges of clinical batch manufacturing and packaging.

Commercial Manufacturing

For turn-key services, UPM also provides large scale commercial capabilities for manufacturing and packaging of tablets and capsule, as well as semi-solid creams and ointments. If needed, suites are available for handling of potent compounds, and moisture sensitive compounds. Handling of DEA controlled substances is available across all UPM’s services, from obtaining quota and storage to manufacturing and packaging.

Packaging & Warehousing

UPM has high speed capabilities for packaging of tablets and capsules into bottles, and packaging of semi-solids into tubes and jars. The solid dosage packaging lines have vibratory bowl and slat fillers. In addition to on-site storage, UPM has a separate facility with an additional 300,000 square feet of warehousing services including storage of DEA controlled substances.