(423) 989-8000     info@upm-inc.com

Professional Careers

UPM is a service organization and our employees are our greatest asset. This is why we seek highly skilled and highly motivated individuals to become a part of our team. We look for people that share a passion for the pharmaceutical industry as well as for hard work, creativity, and growth. Our employees are devoted to our mission of rapidly advancing pharmaceutical technologies and products on behalf of our clients. At the same time, we work in an enriching environment, work as a team where initiative and performance is rewarded. If you share our commitment to teamwork, enjoy a challenge, and want to feel good about the work you do, please contact UPM at humanresources@upm-inc.com to discuss our current open positions.

UPM offers:

  • Health and Dental Insurance
  • Life/Disability Insurance
  • Competitive Salaries
  • 401k Program

Pharmaceutical Project Leader

Job Posted: 04-25-2016

(Senior Director, Director, Manager, Coordinator title depending on experience)

UPM Pharmaceuticals, Inc., (upm-inc.com) a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Pharmaceutical Project Leader.

Essential Duties and Responsibilities:  The project leader, an experienced formulation and process development scientist with project leadership experience in pharmaceutical product development. Will have comprehensive responsibility to lead client projects in various product development and manufacturing activities within time and budget constraints.

Qualifications:

Pharmaceutical experience is required.

Academic study of industrial & physical pharmacy, pharmaceutical chemistry, chemical engineering, chemistry, and biochemistry;  skill in the science & art of pharmaceutical product development;  experience & knowledge of pre-formulation, formulation development, clinical manufacturing, analytical testing, quality control & assurance, cGMP, & GLP;  knowledge of programs like Outlook, Word, Excel, and Access;  detail oriented, a self-starter, excellent organization & communication skills;  ability to handle multiple tasks involving various departments in a fast-paced environment;  effective interpersonal skills;  ability to read, analyze, interpret, & write scientific documents/reports;  the will & ability to achieve success.

Qualified candidates please submit your resume and salary requirements to:  humanresources@upm-inc.com

EOE

Inquire about This Job >>

Technical Services Engineer

Job Posted: 04-21-2016

UPM Pharmaceuticals, Inc., (upm-inc.com) a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Technical Services Engineer.

The role will be responsible for:

  • Execution of equipment / facility qualifications,
  • Assisting with the transfer of products either from internal or external development into the Bristol site;
  • Preparing protocols and reports to document technical for the transfer of products, qualifications, etc. to support Engineering activities.

Essential Duties and Responsibilities:

Reviews/Revises Master Batch Records for clinical/commercial production. Participates on teams transferring products to Bristol or between contract sites.  Evaluates and develops process improvements for manufacturing processes. Supports changes in scale of processes to Manufacturing size including equipment sizing, formulation and equipment compatibility. Prepares equipment equivalency report for regulatory filings and recommends equipment purchases for new processes and to improve existing processes. Prepares, reviews, edits and executes validation documents (IQ, OQ and PQ). Provides manufacturing input to project time-lines for product transfers. Works with QA, Validation, Engineering, Purchasing, Regulatory, R & D and Manufacturing on projects. Prepares suitable protocols and reports on rojects/activities. Partner with Manufacturing and Quality organizations in daily operations to ensure the process is maintained in a GMP compliant, reliable state of control.  Perform process monitoring using a variety of data analysis methods and techniques (e.g., excel, JMP, etc). Participate in and provide technical support and analysis for the resolution of deviations, investigations, and process issues. Generate documents (technical memos, reports, protocols, etc.) related to process monitoring program and non-conformances.

Qualifications:

Pharmaceutical experience is required.

BS in Industrial Pharmacy, Chemical, Engineering, Chemistry or a science related field with six to eight years’ of direct pharmaceutical experience; or equivalent combination of education and direct pharmaceutical experience. Knowledge of basic math, algebra, geometry, calculus and statistics. Thorough knowledge of cGMPs and internal SOPs. Knowledge of pharmaceutical formulations and scale up principles. Extensive knowledge of equipment used in pharmaceutical manufacturing and packaging. Knowledge of validation in pharmaceutical manufacturing and statistical analysis of processes.

Qualified candidates please submit your resume and salary requirements to:  humanresources@upm-inc.com

EOE

Inquire about This Job >>

Pharmaceutical Manufacturing Quality Assurance Associate

Job Posted: 04-06-2016

UPM Pharmaceuticals, a Division of Gregory Pharmaceutical Holdings, Inc., located in Bristol, Tennessee, is seeking to fill a Manufacturing Quality Assurance position that directs and performs activities ensuring quality assurance, cGMP, FDA and internal compliance support to pharmaceutical manufacturing floor operations.

Essential Duties and Responsibilities:

Primary responsibilities require real-time Quality Assurance support to pharmaceutical manufacturing floor operations. Ensures manufacturing and packaging operations conform to established standards and specifications. Participates in batch record review and evaluation, daily monitoring of manufacturing operations, and audits as assigned. Proficient in manufacturing operations and quality procedures to facilitate compliance to regulations. Assists and supports the manufacturing and packaging staff in detecting and solving compliance concerns in real-time during operations. Participates in understanding failures and resulting corrective and preventative actions. Evaluates information from attribute inspections. Participates in, or responds to, quality audits when applicable to assure conformance with regulatory and internal requirements. Revises, evaluates and approves SOPs, Batch Records as necessary. Knowledge of 21 CFR 210 and 211 cGMPs and part 11 to determine disposition of product batches and raw materials. Listens carefully; able to express complex ideas in a clear, concise manner; capable of explaining technical issues to non-technical personnel. Writes clear, accurate, concise technical and non-technical documents.

Education/Experience:

Bachelor’s degree or equivalent experience with at least 5 years of quality assurance experience. Pharmaceutical experience is required. Equivalent combination of education and experience is acceptable. Knowledge of company SOPs, cGMP practices, and FDA regulations essential. Should possess basic computer skills with knowledge of Word, Excel, Access, Outlook and the ability to use internet tools.

Qualified candidates please reference job title and email resume and salary requirements to:

humanresources@upm-inc.com

Or fax: 423-989-8042.

EOE.

Inquire about This Job >>

Analytical Chemist

Job Posted: 03-16-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking an Analytical Chemist.

Under the direction of analytical services management, performs analytical method transfer, optimization, development, and validation.  Performs chemical testing following developmental protocols or approved methods, and participates in instrument validation.  Conducts experiments using wet chemistry and appropriate laboratory instruments, collecting and interpreting analytical data and writing reports in accordance with laboratory SOPs.

Essential Duties and Responsibilities:

Performs analytical method transfer, optimization, development, and conducts analytical methods validation of drug substances, drug product, and residual testing, using guidelines from USP and ICH.   Develops protocols under which the methods transfer, optimization development, and validation are conducted.  Evaluates statistically the validation data and writes the method validation report for submission.  Writes test methods into company SOPs; reviews, writes, or assists in writing SOPs for analytical development.  Performs USP Compendial testing and other Compendial testing as required.  Consults with scientific professionals and scientific literature for problem solving assistance.  Provides analytical testing support for manufacturing process validation.  Documents laboratory activity and files all data using appropriate log books, records, files, and equipment calibration logs.  Operates laboratory equipment such as balances, pH-meters, hardness testers, and dissolution baths in the performance of required and scheduled test procedures, and in accordance with laboratory SOPs.  Performs routine sample processing and dosage form analysis using HPLC, GC, UV-Vis, and other analytical instrumentation.  Collates test results and prepares certificates of analysis and stability reports. Conducts peer review of other analytical chemists and scientists work, prior to submission to quality assurance.

Technical Skills – Ability to operate analytical balance, computer, HPLC, GC, UV/VIS Spectrophotometer, pH meter, FTIR, Karl Fischer Titrator, Automatic Titrator, Polarimeter, Specific Gravity Meter, and Melting Point Apparatus, and other modern analytical equipment.

Education/Experience:

Bachelor’s degree in Chemistry or related scientific field with at least 2 years of analytical chemical experience.  Pharmaceutical laboratory experience preferred.  Equivalent combination of education and experience or training is acceptable.

Computer Skills:

To perform this job successfully, an individual should have computer skills with knowledge of Word, Excel, Access, Outlook, and ability to use internet tools.

Please submit your resume and salary requirements to: humanresources@upm-inc.com or fax: 423-989-8042. EOE.

Inquire about This Job >>

Senior Scientist

Job Posted: 03-16-2016

UPM Pharmaceuticals, a Division of Gregory Pharmaceutical Holdings, Inc., (www.upm-inc.com) located in Bristol, Tennessee, is seeking a Senior Scientist that leads in the development of new analytical methods and mentors other analysts to develop their technical skills.

 Essential Duties and Responsibilities:

Performs analytical method transfer, optimization, and development/validation design and analytical methods development/validation of drug substances, drug product and residual testing, using guidelines from USP and ICH.  Plays a lead role in the development of new methods.  Develops protocols under which the methods transfer, optimization, and development are conducted.  Evaluates statistically the validation data and writes the method validation report for submission.  Writes, edits, and revises test methods and procedures into company SOPs; reviews, writes, or assists in writing SOPs for analytical development.  Participates in the planning and execution of raw material, components, and vendor qualification or alternate supplier qualification studies.  Participates in laboratory investigations and assists in writing investigation reports.  Performs USP Compendial testing and other Compendial testing as required.  Consults with scientific professionals and scientific literature for problem solving assistance.  Provides analytical testing support for manufacturing process validation.  Documents laboratory activity and files all data using appropriate log books, records, files, and equipment calibration logs. Observes safety rules and assists in keeping the laboratory a safe environment.  Operates laboratory equipment such as balances, pH-meters, hardness testers, and dissolution baths in the performance of required and scheduled test procedures and in accordance with laboratory SOPs. Performs routine sample processing and dosage form analysis using HPLC, Dissolution and UV-Vis analysis equipment.  Performs routine maintenance, calibration, and performance verification on applicable instruments.  Conducts peer reviews of other analytical chemists and scientist’s work prior to submission to quality assurance.  Maintains professional and scientific competence in analytical chemistry by reading scientific literature and/or attending seminars, training sessions, workshops or classes.

 Qualifications:

Education/Experience:

Bachelor’s degree in Chemistry or related scientific field with at least 8 years of analytical chemistry experience.  Advanced degree preferred.  Pharmaceutical laboratory experience in analytical methods development and validation is required.  Equivalent combination of education and experience or training is acceptable.  Knowledge of company laboratory SOPs, good laboratory practices, cGMP practices, USP methodology, FDA, ICH, OSHA, and DEA regulations, and MSDSs essential.  Should possess basic computer skills with knowledge of Word, Excel, Access, Outlook and the ability to use internet tools.

Qualified candidates please reference job title and email resume and salary requirements to:

humanresources@upm-inc.com or fax: 423-989-8042. EOE.

Inquire about This Job >>