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Professional Careers

UPM is a service organization and our employees are our greatest asset. This is why we seek highly skilled and highly motivated individuals to become a part of our team. We look for people that share a passion for the pharmaceutical industry as well as for hard work, creativity, and growth. Our employees are devoted to our mission of rapidly advancing pharmaceutical technologies and products on behalf of our clients. At the same time, we work in an enriching environment, work as a team where initiative and performance is rewarded. If you share our commitment to teamwork, enjoy a challenge, and want to feel good about the work you do, please contact UPM at humanresources@upm-inc.com to discuss our current open positions.

UPM offers competitive salaries and an excellent benefit package.  To learn more, click here to download our Benefit Summary. 

Microbiologist I

Job Posted: 12-01-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking an Analytical Chemist.

This position performs routine microbiological quality control testing of pharmaceutical products and related materials in accordance with site policies, departmental procedures, compendial methods and cGMP regulations.  Participates in programs to achieve departmental objectives; records and reports results; notes unusual results and notifies supervision for evaluation.

Essential Duties and Responsibilities:

The essential functions of this position may include, but are not limited to:

  • Performs routine microbiological testing of raw material, in process, finished product and stability following approved specifications and Standard Operating Procedures (SOPs). This may include but is not limited to antibiotic testing, bioburden/microbial limit testing, antimicrobial effectiveness testing, water testing, environmental monitoring, microbial isolation and identification technique, sterility and endotoxin testing.
  • Completes testing with a high degree of efficiency, reliability, and accuracy
  • Learns to and maintains the Microbiology Laboratory. This may include but is not limited to maintenance, calibration and use of standard laboratory equipment.
  • Logs samples received into the laboratory and assess their integrity upon receipt.
  • Performs assigned work in a timely and safe manner conforming to regulatory, company and compendial requirements.
  • Records and reports test data correctly, completely and accurately within company and departmental policies and guidelines. Notifies supervision of unusual results for evaluation.
  • Actively assumes and demonstrates responsibility in learning practical laboratory skills, and a thorough knowledge of microbiological theories, methodologies and procedures.
  • Acquires knowledge and understanding of company and departmental policies pertaining to cGMP, cGLP, safety, health, security, and departmental operation. Complies with company and departmental regulations, policies and guidelines in performances of the job.
  • Recognizes problems within the scope of the job and promptly and clearly communicates them to supervision. Follows directions and demonstrates proper judgment when a deviation occurs.
  • Initiates Laboratory Investigation Reports (LIRs) and Notices of Events (NOEs). Reviews out of specification (OOS) and unusual test/equipment data with management of senior staff and complete LIRs and NOEs under the direction of management and advisement of senior staff members.
  • Learns to and recognizes trends, deviations, problems, and promptly reports them to laboratory management. Follows directions and demonstrates proper judgment when a deviation occurs.
  • Participates in inventory control. Maintains a neat and orderly workspace, adhering to all laboratory disinfection policies.

Education/Experience:

Bachelor’s Degree in Microbiology or related science field and 0-2 years of related experience; or an equivalent combination of education and experience/training; advanced degree in Chemistry or closely related field is desirable, but not required; some laboratory experience is desirable.

EOE.

 

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Analytical Chemist

Job Posted: 12-01-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking an Analytical Chemist.

Under the direction of analytical services management, performs analytical method transfer, optimization, development, and validation.  Performs chemical testing following developmental protocols or approved methods, and participates in instrument validation.  Conducts experiments using wet chemistry and appropriate laboratory instruments, collecting and interpreting analytical data and writing reports in accordance with laboratory SOPs.

Essential Duties and Responsibilities:

Performs analytical method transfer, optimization, development, and conducts analytical methods validation of drug substances, drug product, and residual testing, using guidelines from USP and ICH.   Develops protocols under which the methods transfer, optimization development, and validation are conducted.  Evaluates statistically the validation data and writes the method validation report for submission.  Writes test methods into company SOPs; reviews, writes, or assists in writing SOPs for analytical development.  Performs USP Compendial testing and other Compendial testing as required.  Consults with scientific professionals and scientific literature for problem solving assistance.  Provides analytical testing support for manufacturing process validation.  Documents laboratory activity and files all data using appropriate log books, records, files, and equipment calibration logs.  Operates laboratory equipment such as balances, pH-meters, hardness testers, and dissolution baths in the performance of required and scheduled test procedures, and in accordance with laboratory SOPs.  Performs routine sample processing and dosage form analysis using HPLC, GC, UV-Vis, and other analytical instrumentation.  Collates test results and prepares certificates of analysis and stability reports. Conducts peer review of other analytical chemists and scientists work, prior to submission to quality assurance.

Technical Skills – Ability to operate analytical balance, computer, HPLC, GC, UV/VIS Spectrophotometer, pH meter, FTIR, Karl Fischer Titrator, Automatic Titrator, Polarimeter, Specific Gravity Meter, and Melting Point Apparatus, and other modern analytical equipment.

Education/Experience:

Bachelor’s degree in Chemistry or related scientific field. At least two years of analytical chemical experience preferred.  Pharmaceutical laboratory experience preferred.  Equivalent combination of education and experience or training is acceptable.

Computer Skills:

To perform this job successfully, an individual should have computer skills with knowledge of Word, Excel, Access, Outlook, and ability to use internet tools.

Please submit your resume and salary requirements to: humanresources@upm-inc.com or fax: 423-989-8042.

EOE.

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Mechanic (Packaging)

Job Posted: 10-05-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Mechanic (Packaging).

Summary:

The mechanic is responsible for machine repair, Install, adjustments, and maintaining pharmaceutical processing machinery. Performs routine maintenance, troubleshooting, and repair of various equipment within the packaging department.

Essential Duties and Responsibilities:

  • Disassemble machinery and equipment to remove parts and make repairs.
  • Examine parts for defects such as breakage and excessive wear.
  • Repair and replace broken or malfunctioning components of machinery and equipment.
  • Clean, lubricate and adjust parts, equipment and machinery.
  • Reassemble equipment after completion of inspections, testing or repairs.
  • Assist maintenance personnel in repair of equipment.
  • Perform set-ups of manufacturing and packaging equipment in according with SOPs and equipment specifications.

Education/Experience:

  • Knowledge of processes related to the production of solid dose pharmaceutical manufacturing.
  • The ability to distinguish the proper type of tool to be used for a specific job.
  • The ability to quickly and repeatedly adjust the controls of a machine or a vehicle to exact positions.
  • High School Diploma or GED required.
  • Knowledge of cGMP practices required.
  • Knowledge of operation of technical equipment required.

Other information:

  • 1 dayshift position available; Hours are M-F, 7:30a – 4p
  • 2 evening shifts available; Hours are M-F, 3:30p – 12a

Please submit your resume and salary requirements to: humanresources@upm-inc.com  

EOE

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Technical Services Process Scientist

Job Posted: 09-30-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Technical Services Process Scientist.

The role will be responsible for:

  • Scale-up, tech transfer, and process development of tablet and capsule products.
  • Execution of equipment and facility qualifications and process validations.
  • Process optimization, trouble-shooting, investigation, and support for commercial manufacturing.
  • Writing manufacturing records, development plans, protocols, and reports for process development, equipment qualification, process validation, deviations, and investigations.

Essential Duties and Responsibilities:

Technology transfer of solid dose products into Bristol site commercial manufacturing.  Site transfer of existing commercial products; scale-up and process development for new formulations.  Prepare equipment equivalency reports for regulatory filings; recommend equipment purchases for new processes and to improve existing processes.  Work with QA, Validation, Engineering, Purchasing, Regulatory, R & D, and Manufacturing on project teams.  Write, review, and execute validation protocols (equipment IQ, OQ, and PQ; process validations).  Provide technical support to Manufacturing for the resolution of deviations, investigations, and process issues. Perform process monitoring using statistical analysis.  Evaluate and develop process improvements for manufacturing processes. Write Master Batch Records, development reports, investigation reports.

Qualifications:

Pharmaceutical experience is required.

BS in Industrial Pharmacy, Chemical, Engineering, Chemistry or a science related field with six to eight years’ of direct pharmaceutical experience; or equivalent combination of education and direct pharmaceutical experience. Essential skills are knowledge of solid-dose unit operations, problem-solving ability, technical writing, project management, and ability to learn on the job.  Knowledge of cGMPs and internal SOPs.  Knowledge of pharmaceutical formulations and scale-up principles. Extensive knowledge of tablet and capsule process equipment and unit operations. Knowledge of current FDA validation requirements.  Experience with controlled substances is preferred.  Experience with Wurster processing is preferred.  Experience with formulation of tablets and capsules is preferred.

Qualified candidates please submit your resume and salary requirements to:  humanresources@upm-inc.com

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Manufacturing Operator

Job Posted: 09-20-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Manufacturing Operator.

The Manufacturing Operator performs manufacturing processes of solid dose tablets and capsules, and liquid dose, in accordance with SOPs, approved batch records, and cGMP procedures.

Essential Duties and Responsibilities:

  • Weighs and samples development and commercial manufacturing batches in accordance with applicable SOPs.
  • Sets up, operates, breaks down and cleans equipment to be used in manufacturing activities in accordance with SOPs and equipment specifications.
  • Performs scheduled manufacturing activities in accordance with approved batch records.
  • Performs appropriate in-process tests of manufactured products during the manufacturing process.
  • Provides appropriate documentation of manufacturing processes and test results including maintaining and reconciling equipment and room use log books, batch records, and inventory records in accordance with SOPs.
  • Performs appropriate cleaning of equipment and the facility in accordance with SOPs and cGMP procedures.
  • Troubleshoots equipment/processes during the manufacturing process.
  • Performs other duties as assigned.

Knowledge Necessary to Perform the Job:

  • Moderate knowledge of cGMP practices required.
  • Moderate knowledge of operation of technical equipment required.
  • Knowledge of processes related to the production of solid dose pharmaceutical manufacturing REQUIRED.
  • Knowledge of process related to the production of liquid dose pharmaceutical manufacturing required.
  • Knowledge of electronic data acquisitions systems to include ADP, Documentum, and FormWeigh.

Education/Experience:

High School Diploma or GED required.

Please submit your resume and salary requirements to: humanresources@upm-inc.com  

EOE

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Formulation Associate

Job Posted: 07-19-2016

UPM Pharmaceuticals, Inc., a contract drug development and manufacturing company for the pharmaceutical industry, located in Bristol, Tennessee, is seeking a Formulation Associate.

Formulation Associate:  a hands-on support scientist role in pharmaceutical formulation and process development. Will have responsibility to support client projects in various product development and manufacturing activities within time and budget constraints.

Desired attributes include:  academic study of industrial & physical pharmacy, pharmaceutical chemistry, chemical engineering, chemistry, and biochemistry;  skill in the science & art of pharmaceutical product development;  experience & knowledge of pre-formulation, formulation development, clinical manufacturing, analytical testing, quality control & assurance, cGMP, & GLP;  knowledge of programs like Outlook, Word, Excel, and Access;  detail oriented, a self-starter, excellent organization & communication skills;  ability to handle multiple tasks involving various departments in a fast-paced environment;  effective interpersonal skills;  ability to read, analyze, interpret, & write scientific documents/reports;  the will & ability to achieve success.

Qualified candidates please reference job title and email resume and salary requirements to: humanresources@upm-inc.com

EOE

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Senior Scientist

Job Posted: 03-16-2016

UPM Pharmaceuticals, a Division of Gregory Pharmaceutical Holdings, Inc., (www.upm-inc.com) located in Bristol, Tennessee, is seeking a Senior Scientist that leads in the development of new analytical methods and mentors other analysts to develop their technical skills.

 Essential Duties and Responsibilities:

Performs analytical method transfer, optimization, and development/validation design and analytical methods development/validation of drug substances, drug product and residual testing, using guidelines from USP and ICH.  Plays a lead role in the development of new methods.  Develops protocols under which the methods transfer, optimization, and development are conducted.  Evaluates statistically the validation data and writes the method validation report for submission.  Writes, edits, and revises test methods and procedures into company SOPs; reviews, writes, or assists in writing SOPs for analytical development.  Participates in the planning and execution of raw material, components, and vendor qualification or alternate supplier qualification studies.  Participates in laboratory investigations and assists in writing investigation reports.  Performs USP Compendial testing and other Compendial testing as required.  Consults with scientific professionals and scientific literature for problem solving assistance.  Provides analytical testing support for manufacturing process validation.  Documents laboratory activity and files all data using appropriate log books, records, files, and equipment calibration logs. Observes safety rules and assists in keeping the laboratory a safe environment.  Operates laboratory equipment such as balances, pH-meters, hardness testers, and dissolution baths in the performance of required and scheduled test procedures and in accordance with laboratory SOPs. Performs routine sample processing and dosage form analysis using HPLC, Dissolution and UV-Vis analysis equipment.  Performs routine maintenance, calibration, and performance verification on applicable instruments.  Conducts peer reviews of other analytical chemists and scientist’s work prior to submission to quality assurance.  Maintains professional and scientific competence in analytical chemistry by reading scientific literature and/or attending seminars, training sessions, workshops or classes.

 Qualifications:

Education/Experience:

Bachelor’s degree in Chemistry or related scientific field with at least 8 years of analytical chemistry experience.  Advanced degree preferred.  Pharmaceutical laboratory experience in analytical methods development and validation is required.  Equivalent combination of education and experience or training is acceptable.  Knowledge of company laboratory SOPs, good laboratory practices, cGMP practices, USP methodology, FDA, ICH, OSHA, and DEA regulations, and MSDSs essential.  Should possess basic computer skills with knowledge of Word, Excel, Access, Outlook and the ability to use internet tools.

Qualified candidates please reference job title and email resume and salary requirements to:

humanresources@upm-inc.com or fax: 423-989-8042. EOE.

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