Formulation Development

UPM has extensive experience and expertise in the development of solid oral dosage forms, including controlled and immediate release formulations. Formulation development capabilities include blending, high shear granulation, fluid bed granulation, extrusion-spheronization, roller compaction, bi-layer compression, mini-tablets, encapsulated tablets and beads, coated tablets.  UPM also has expertis with development, testing, formulation and manufacture of semi-solid drugs, including creams and ointments.

Formulation Evaluation

Formulation development has been one of the key services UPM has offered since its inception at the University of Maryland. Our experienced and professional scientists thoroughly enjoy providing industry standard and unique solutions for our clients and their respective drug development programs. UPM’s formulation evaluation services for solid oral and semi-solid creams and ointments include:

  • Content Uniformity Evaluation
  • Dissolution Testing
  • Stability Assessment
  • In-vitro Bioequivalence Determination
  • Powder Flow Determination
  • Compressibility Evaluation
  • Disintegration Testing
  • Friability Testing
  • Tap Density Testing
  • DOE

Dosage Forms and Processes

  • Solid and Semi-Solid Formulation Development
  • Immediate Release Tablet and Capsule Formulations
  • Controlled Release Tablets and Capsule Formulations
  • Mini-Tablets / Bilayer Tablets
  • Fast Oral Disintegrating Tablet Formulations
  • Matrix and Coating Formulations
  • Wet and Dry Granulations
  • Low Dose Content Uniformity
  • High Dose Compressibility
  • Full Support from Concept to Commercialization

The R&D group works closely with the analytical group to ensure the appropriate testing, method development, and timeliness is maintained for each Client development program.