Technical Services

UPM Pharmaceuticals has extensive experience and expertise in the development of solid oral dosage forms, including modified and immediate release formulations. Formulation development capabilities include blending, high shear granulation, fluid bed granulation, Wurster coating, extrusion-spheronization, roller compaction, bi-layer compression, mini-tablets, encapsulated tablets and beads, coated tablets.  UPM also has expertise with development, testing, formulation and manufacture of semi-solid drugs, including creams and ointments.

Formulation Evaluation

Formulation evaluation has been one of the key services UPM has offered since its inception at the University of Maryland. Our experienced and professional scientists thoroughly enjoy providing industry standard and unique solutions for our clients and their respective drug development programs. UPM’s formulation evaluation services include:

  • Content Uniformity Evaluation
  • Potency
  • Dissolution Testing
  • Stability Assessment
  • In-Vitro Dissolution Profile Evaluation
  • Powder Flow Determination
  • Compressibility Evaluation
  • Disintegration Testing
  • Friability Testing
  • Tap Density Testing
  • Particle Size Testing
  • Micro Testing

At UPM Pharmaceuticals, our scientists approach each formulation project with the commercial product in mind.

Dosage Forms and Processes

  • Solid and Semi-Solid Formulation Development
  • Immediate Release Tablet and Capsule Formulations
  • Modified Release Tablets and Capsule Formulations
  • Mini-Tablets / Bi-Layer Tablets
  • Oral Disintegrating Tablet Formulations (ODT)
  • Modified Release and Cosmetic Tablet Coatings
  • Wet and Dry Granulations
  • Low Dose Capsule and Tablet Formulation
  • High Dose Capsule and Tablet Formulation
  • Full Support from Transfer to Commercialization

The Technical Services works closely with the analytical development group to ensure the appropriate testing, method development, and timeliness is maintained for each client development program.

Formulation Equipment

  • Mini-Glatt
  • V-Blender
  • Quadro Co-Mill
  • Fruend Vector-Roller Compactor and Rotary Granulator
  • Diosna High Shear Mixer
  • Vector Granulator
  • Retsch-Ball Mill
  • Fitz Mill
  • Caleva Mini Extruder and Spheronizer
  • Schaefer Lab Cap Encapsulator
  • Fruend Vector LDCS Hi-Coater (Tablet Pan Coater)
  • Styl'One Single Station Tablet Press