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BREVI-BATCH® processing platform

UPM Pharmaceuticals BREVI-BATCH Services Glatt MiniBREVI-BATCH® processing platform for solid dose mini-scale R&D formulation development batches. The new platform is ideal for clients seeking fast, low cost, but high quality proof-of-concept results before they invest significant dollars in cGMP development. The target batch size using the mini-scale processing equipment is 100 grams. This scale is significantly smaller than most small scale R&D formulation batches and will conserve client’s valuable R&D API. Furthermore, the equipment is designed for fast set-up and clean-up, and depending on the API toxicity, all processing can be done under containment conditions. UPM sees this service as essential to our clients who are trying to make the best and most cost effective decisions about investment of precious research funds. By making smaller research commitments earlier in the process, companies can engage in a cost effective but high quality development process.

Equipment Highlights:

Quadro Comill U5

UPM Pharmaceuticals roller compactor equipment

  • 40g sample size
  • Over 200 diferent screens and dozens of impellers

Caleva Screen Extruder

  • Screen from 0.5-2.5mm
  • Processing rates or up to 20 kg per hour

Caleva MBS Spheronizer 120

  • Working capacity from 10 to 150 g
  • For limited or expensive material

L1A Fitzmill

  • Process as little as 5g with minimal loss
  • Process wet or dry products

Vector Freund TFC-Lab Micro Roller Compactor

  • Minimum sample size of 5 g
  • Up to 1kg per hour working capacity

Mini Glatt

  • Top Spray 50-750 ml
  • Bottom Spray 150-600ml
  • Standard container for 50-350 g and MicroKit for 2.5-50 g

Diosna P 1-6 High Shear Lab Mixer

  • 0.25, 0.5, 1, 2, 4, 6 liter stainless steel vessels
  • Reproducible mixing and granulating

PK Blendmaster V-Blender

  • 0.5, 1, and 2 shell sizes (quart)
  • 24 rpm Blender speed

Vector Freund LCDS Hi-Coater

  • 0.5, 1.5, 2.5, 4, 6, and 8 liter pan sizes
  • 34-100 m3 per hour at 25 – 100°C
  • Spray gun rate 5-30 ml per minute

M&O Perry Accodil Model FC

  • Fills from 2mg to 250 g

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