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Equipment Summary

UPM’s 475,000 sq foot main facility in Bristol, Tennessee features a broad range of equipment to satisfy the needs of its pharmaceutical and biotech clients. The equipment addresses both routine and complex development and manufacturing challenges for solid oral capsules and tablets, and semi solid creams and ointments.  The equipment scale can take Client product from concept through commercialization. UPM also has the ability to package these final dosage forms via high speed and packaging lines.

  • Sty’lOne Multi-Layer – R&D only
  • Korsch 100KL tablet press – 10,000/hr
  • Fette 1200 (2) – 80,000/hr
  • Fette 2090 – 90,000/hr
  • Fette 2200 – 100,000/hr
  • Fette 3200 – 500,000/hr
  • Manesty Diamond (3) – 500,000/hr
  • Fette 52i Single/Bi-Layer – 24-48,000/hr
  • Mini-Glatt w Microkit Insert – 5-350g, R&D only
  • R&D mini-coater – 35 grams; R&D only
  • Glatt GPCG-2 – 0.75-2 Kg
  • Glatt GPCG- 30/60 – 15 K-60 Kg
  • FBE 500 Combo – 150 Kg, 250 Kg
  • Diosna P1-6 high shear – 50 grams R&D only
  • Niro Felder GP-1 – 1-3 Kg
  • SeJong SM-50L High Shear Granulator – 15-20 Kg
  • PMA 150L High Shear Granulator – 40-60 Kg
  • PMA 800L High Shear Granulator – 150-300 Kg
  • AMF Mixer – 5-125 Kg
  • Littleford Mixer 600L – 100-200Kg
  • Capsugel CFS-1200w/ LEMS – 1,200/hr
  • Qualicaps F 40 – 40,000/hr
  • Capsugel LEMS – 70 Sealer – 60,000/hr
  • Lightning XL Mixer – propeller mixers
  • Cole Palmer Servodyne – propeller mixers
  • Market Forge Tank – 20 gallon (80L)
  • Keith Tank – 620L
  • Ekato LM6 – 6L
  • Ekato SRT-80 – 80L
  • Scott Turbon – 65L, 100L, 200L
  • Lee Kettles – 100, 200, 300, 500 gal
  • Keith Model SPFS Liquid Filler – 60 bottles/hr
  • Fillamatic SYN-8-4 – 720 bottles/hr
  • Feton Capsule Fillers – 2000/shift
  • ShinogiQualifil Model 8S – 1,500-3,000/hr
  • CapsugelXcelodose 600 (2) – 150-300/hr
  • CapsugelXcelodose 600S (2) – 150-300/hr
  • ACG AFT-Lab – 6,000/hr
  • Schafer Incap – 2-3,000/hr
  • MG Planeta 50 – 50,000/hr
  • MG2 140 – 100,000/hr
  • MG Suprema – 50,000/hr
  • Perry Accofil – 1,000/shift w/2 operator
  • Silverson L5M-A – in-line mixer 1 ml-12 liters
  • BEE International Micro DeBee – up to 25L/hr; 20 ml minimum
  • IKA Labor pilot 2000/4 Colloid Wet Mill – gallon batches
  • FoodPharma Jet Mill – 250g/hr
  • Fitzpatrick DAS06 – Continuous feed
  • Fitzmill – Continuous
  • Fitzmill L1A – R&D mini
  • Quadro Co-mill 194S, 196S, 197S,U5 – Continuous feed
  • Retsch Mixer-mill ball mill – 50g/batch, 1Kg/hr
  • SWECO Sieve – continuous feed
  • UPLC / HPLC capability
  • Dissolution testing
  • Full ICH stability conditions
  • Microbial testing
  • Purity testing
  • Impurity identification
  • Particle size determination by laser
  • Excipient compatibility testing
  • Solubility screening
  • Hygroscopicity studies
  • Methods qualification and validation
  • Controlled drug substances testing (CII–CV)
  • GC / headspace analysis
  • Cascade Tek TFO-3 Drying Ovens (2) – 1-8 Kg
  • Aeromatic T-7 Dryer – 150-300 Kg
  • Lydon Drying Ovens (5) – ~150Kg/oven
  • Safeline Metal Detector (4)
  • CPT-200 Deduster/Polish (2)
  • Key TD101-WD (2)
  • LCI SADE- 140 weight sorter (2) – 4,000/hr
  • Key and Distek GD-2 Disintegration tester
  • Flow-dex
  • Logan TP2 tap density
  • Erweka AR200 Friabilator
  • CWI 90 Qualicaps Weight Sorter (2) – 90,000/hr
  • Vector Freund TFC Lab-micro Roller Compactor – 5 gram mini batch; up to 1Kg/hr; R&D only
  • Alexanderwerk WP 120×40 Roller Compactor – 1-5 Kg/hr
  • Fitzpatrick Chilsonator – 10-25 Kg/hr
  • V-Blenders – 0.5, 1, 2, 4, 8, 16 qt; 1, 3, 5, 10, 20, 40, 75 cu ft (40 & 70 have no intensifier bar capability)
  • Bin Blenders – 128,320,800, 2150L
  • Ribbon Blender – 150 Kg /300L: 120Kg /100L: 40Kg
  • Ohara 15”,19”,30” – 5-30Kg
  • Accela Cota Coater 48” – 125Kg
  • Coy Laboratory Products Isolation Glove Box – Small scale pharmaceutical work ( < 5 kilo batch size)
  • Form Weigh – Materials management system; inventory, bar code w/ labels
  • Documentum – Electronic controlled documentation system
  • E-room – Client secure posting of documents
  • Blue Mountain – Calibration software
  • Novatech – Stability management software, FDA filing compliant
  • Statgraphics – Statistics package for DoE and QbD
  • (2) Flow Sciences Model FS 2024 BKDVA Ventilated Work Stations
  • Manual line for bottles
  • Automated Packaging Lines for bottles (3) – 60-100/ minute
  • Automated Packaging line for semi-solids for tubes and jars
  • Bellatrix Vibratory Line – 10-60 bottles/minute